Yan Ji Selected Research

Therapeutics

3/2024	Ribociclib plus Endocrine Therapy in Early Breast Cancer.
3/2024	Utility and impact of quantitative pharmacology on dose selection and clinical development of immuno-oncology therapy.
12/2023	Quantitative Assessment of Ribociclib Exposure-Response Relationship to Justify Dose Regimen in Patients with Advanced Breast Cancer.
1/2023	Targeting KRAS-mutant stomach/colorectal tumors by disrupting the ERK2-p53 complex.
12/2022	EBV promotes vascular mimicry of dormant cancer cells by potentiating stemness and EMT.
3/2022	Updated Overall Survival of Ribociclib plus Endocrine Therapy versus Endocrine Therapy Alone in Pre- and Perimenopausal Patients with HR+/HER2- Advanced Breast Cancer in MONALEESA-7: A Phase III Randomized Clinical Trial.
1/2022	Mesenchymal and stem-like prostate cancer linked to therapy-induced lineage plasticity and metastasis.
10/2020	Evaluation of Absolute Oral Bioavailability and Bioequivalence of Ribociclib, a Cyclin-Dependent Kinase 4/6 Inhibitor, in Healthy Subjects.
9/2020	Ribociclib, a CDK 4/6 inhibitor, plus endocrine therapy in Asian women with advanced breast cancer.
7/2020	Blood Outgrowth Endothelial Cells as a Cellular Carrier for Oncolytic Vesicular Stomatitis Virus Expressing Interferon-β in Preclinical Models of Non-Small Cell Lung Cancer.

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Yan Ji Research Topics

Disease

29	Neoplasms (Cancer) 03/2024 - 12/2003
19	Breast Neoplasms (Breast Cancer) 03/2024 - 10/2004
17	Inflammation (Inflammations) 09/2023 - 01/2008
8	Carcinogenesis 10/2018 - 10/2004
7	Infections 03/2024 - 07/2008
5	Body Weight (Weight, Body) 01/2024 - 01/2007
4	Neutropenia 01/2024 - 09/2020
4	Neoplasm Metastasis (Metastasis) 01/2023 - 11/2021
4	Ischemic Stroke 08/2022 - 10/2013
4	Cataract (Cataracts) 06/2020 - 01/2017
4	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 03/2017
3	Myopia 01/2022 - 12/2014
3	Uveitis 01/2022 - 12/2018
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 07/2020 - 10/2015
3	Obesity 01/2020 - 07/2012
3	Hypoxia (Hypoxemia) 01/2017 - 11/2002
3	Carcinoma (Carcinomatosis) 12/2016 - 10/2004
3	Stroke (Strokes) 01/2015 - 10/2013
3	Leukemia 06/2006 - 05/2002
2	Virus Diseases (Viral Diseases) 04/2024 - 07/2008
2	Cognitive Dysfunction 02/2024 - 08/2022
2	Autoimmune Diseases (Autoimmune Disease) 11/2023 - 08/2019
2	Chronic Urticaria 09/2023 - 01/2023
2	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2023 - 10/2013
2	Cerebral Small Vessel Diseases 01/2023 - 01/2023
2	Vascular Remodeling 06/2022 - 11/2016
2	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 10/2006
2	Colitis 01/2021 - 01/2019
2	Lung Neoplasms (Lung Cancer) 07/2020 - 11/2019
2	Vesicular Stomatitis 07/2020 - 10/2015
2	Corneal Edema 06/2020 - 12/2019
2	Hypertension (High Blood Pressure) 01/2020 - 12/2018
2	Atherosclerosis 01/2020 - 01/2015
2	Pneumonia (Pneumonitis) 01/2019 - 02/2009
2	Stomach Neoplasms (Stomach Cancer) 10/2018 - 12/2016
2	Hyperplasia 11/2016 - 08/2011
2	Osteoporosis 01/2016 - 11/2014
2	Cerebral Hemorrhage 08/2015 - 08/2013
2	Hemorrhagic Stroke 10/2013 - 10/2013
2	Myeloid Leukemia (Leukemia, Myelocytic) 06/2006 - 10/2005

Drug/Important Bio-Agent (IBA)

12	ribociclibIBA 03/2024 - 01/2020
11	Proteins (Proteins, Gene)FDA Link 12/2023 - 01/2003
9	CytokinesIBA 04/2024 - 01/2008
9	Hormones (Hormone)IBA 03/2024 - 09/2020
6	Biomarkers (Surrogate Marker)IBA 01/2023 - 10/2013
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2023 - 09/2010
5	Messenger RNA (mRNA)IBA 01/2022 - 02/2009
4	Epidermal Growth Factor (EGF)IBA 01/2024 - 10/2020
4	Glucose (Dextrose)FDA LinkGeneric 09/2023 - 01/2019
4	HomocysteineIBA 01/2020 - 10/2013
4	Vitamin D FDA LinkGeneric 10/2006 - 01/2004
3	Aromatase InhibitorsIBA 03/2024 - 01/2021
3	CholesterolIBA 01/2023 - 07/2009
3	Long Noncoding RNAIBA 12/2022 - 12/2016
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020 - 02/2009
3	Plasminogen Activator Inhibitor 1IBA 01/2020 - 08/2011
3	Interleukin-6 (Interleukin 6)IBA 01/2020 - 02/2009
3	RNA (Ribonucleic Acid)IBA 01/2018 - 01/2003
3	LipopolysaccharidesIBA 12/2016 - 07/2009
3	IsothiocyanatesIBA 10/2009 - 12/2004
3	phenethyl isothiocyanate (PEITC)IBA 09/2005 - 12/2003
2	Antiviral Agents (Antivirals)IBA 03/2024 - 07/2020
2	Fulvestrant (Faslodex)FDA Link 01/2024 - 01/2021
2	Advanced Glycation End ProductsIBA 09/2023 - 03/2023
2	ligelizumabIBA 09/2023 - 01/2023
2	Cyclin-Dependent Kinase 4IBA 01/2023 - 10/2020
2	Triglycerides (Triacylglycerol)IBA 01/2023 - 01/2020
2	LipidsIBA 09/2022 - 01/2020
2	Vasoconstrictor AgentsIBA 06/2022 - 01/2019
2	LuciferasesIBA 01/2022 - 10/2018
2	LSZ102IBA 01/2022 - 11/2021
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2021 - 01/2019
2	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2021 - 01/2020
2	ErbB Receptors (EGF Receptor)IBA 01/2021 - 09/2020
2	InterferonsIBA 07/2020 - 10/2015
2	Oxygen (Dioxygen)IBA 01/2020 - 11/2002
2	tiplaxtininIBA 01/2020 - 11/2016
2	NitrogenIBA 01/2020 - 07/2013
2	NF-kappa B (NF-kB)IBA 01/2020 - 01/2008
2	Plasminogen Activators (Plasminogen Activator)IBA 01/2020 - 11/2016
2	Interleukin-17 (Interleukin 17)IBA 08/2019 - 01/2019
2	Peptides (Polypeptides)IBA 01/2019 - 01/2013
2	LigandsIBA 01/2019 - 01/2016
2	AntibodiesIBA 01/2019 - 07/2008
2	ParaquatIBA 01/2017 - 08/2013
2	AntioxidantsIBA 12/2016 - 02/2009
2	CalciumIBA 09/2016 - 01/2015
2	naringinIBA 01/2016 - 11/2014
2	EnzymesIBA 07/2010 - 02/2009
2	1,25-dihydroxyvitamin DIBA 10/2006 - 01/2004
2	Cholecalciferol (Vitamin D3)FDA Link 07/2006 - 05/2002
2	CCAAT-Enhancer-Binding Protein-betaIBA 10/2005 - 01/2004
1	human ERBB2 proteinIBA 03/2024
1	Anastrozole (Arimidex)FDA LinkGeneric 03/2024

Therapy/Procedure

19	Therapeutics 03/2024 - 10/2005
4	Phacoemulsification 06/2020 - 01/2017
2	Drug Tapering 01/2024 - 12/2023
2	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2016 - 12/2014
2	Transplantation 10/2013 - 08/2013
2	Resuscitation 09/2009 - 11/2002